6/20/20: Manga Studio later changed names to Clip Studio. I currently have the Pro version, it's quite nice. I just need to figure out why my tablet pen sensitivity doesn't register on it too well.
11/23/11: How does it look?
Well, I didn't want to spend so much money on Photoshop, so I've been playing with Manga Studio Debut. It's pretty good, so far. My main complaint w/ PS is that I couldn't get the speech bubbles to look right (not that I'm an expert on using it, though). MSD is catered more specifically for comics and manga, so it's pretty nifty. There's even brushes that emulate line thickness, even w/out a tablet. One downside is that I can't adjust the color levels on the Debut version, but even if I buy the full one it'll still be cheaper than PS. It looks a lot cleaner but it does lose some of the traditional media feel. We'll see, I still have to play around w/ it more, especially on a full color page.